MCAT QOTD: Secretin’s Effects
A team of researchers is investigating the impact of secretin on pancreatic bicarbonate secretion. In their experiment, they administer secretin to a group of test subjects and measure bicarbonate levels in pancreatic ductal fluid over time. They compare this to a control group that receives a saline injection. Additionally, to determine the role of pH, the subgroup of the secretin group receives an acidic solution introduced into the duodenum. The researchers hypothesize that secretin’s effect is mediated by the low pH of chyme entering the duodenum.
Which of the following findings would best support the researchers’ hypothesis?
A) The secretin group shows no significant increase in bicarbonate secretion compared to the control group
B) The group receiving both secretin and the acidic solution shows a higher bicarbonate secretion than the group receiving secretin alone
C) The group receiving the acidic solution alone shows no significant change in bicarbonate solution compared to the control group
D) The control group shows the same level of bicarbonate secretion as the group receiving the acidic solution.
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