A Fatal Inheritance
How a Family Misfortune Revealed a Deadly Medical Mystery
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Narrado por:
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Roger Wayne
Acerca de esta escucha
Long-listed, BookPage Best Books of the Year, 2024
National Book Critics Circle Award nominee, 2024
Long-listed, Amazon.com Best Books of the Year, 2024
Long-listed, NPR Best Book of the Year, 2024
"Listeners will find A Fatal Inheritance to be an effective overview of research on cancer and hereditary predisposition, one that achieves serious investigation while remaining intensely human.”—BookPage
Weaving his own moving family story with a sweeping history of cancer research, Lawrence Ingrassia delivers an intimate, gripping tale that sits at the intersection of memoir and medical thriller
Ingrassia lost his mother, two sisters, brother, and nephew to cancer—different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation.
Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s—when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come—to present day, as Ingrassia and countless others continue to unpack and build upon Li and Fraumeni’s initial discoveries, and to understand what this means for their families.
In the face of seemingly unbearable loss, Ingrassia holds onto hope. He urges us to “fight like Charlie,” his nephew who battled cancer his entire life starting with a rare tumor in his cheek at the age of two—and to look toward the future, as gene sequencing, screening protocols, CRISPR gene editing, and other developing technologies may continue to extend lifespans and perhaps, one day, even offer cures.
A Macmillan Audio production from Henry Holt & Company.
©2024 Lawrence Ingrassia (P)2024 Macmillan AudioLos oyentes también disfrutaron...
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Reseñas de la Crítica
“A Fatal Inheritance by Lawrence Ingrassia is a compelling personal chronicle of tragedy and triumph. It captures both the ineffable pain of families riddled with cancers and the remarkable research over the past half century by scientists determined to help them.”—Siddhartha Mukherjee, author of The Emperor of All Maladies: A Biography of Cancer
"When two young doctors came across a family riddled with cancer for generations, they wondered why and began a decades long search for the answer. In A Fatal Inheritance, a riveting narrative of their quest, Lawrence Ingrassia intertwines a deeply personal and tearful story of unbearable family loss with an inspiring story of scientific discovery that revolutionized the understanding and treatment of cancer."—Walter Isaacson, author of Elon Musk, The Code Breaker and Steve Jobs
"When Lawrence Ingrassia lost his mother, sisters, brother and nephew to cancer, was it appallingly bad luck, or was there a common cause? This is the story of a family tragedy, a medical mystery, and the painstaking work of insightful scientists. By turns heartbreaking and hopeful, A Fatal Inheritance is a story of mortal loss and human resilience."—Geraldine Brooks, author of Horse and March
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How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.
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Excellent course
- De Doug B. en 05-23-19
De: Michael E. Wysession, y otros
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Secrets of the Octopus
- De: Sy Montgomery, Warren K. Carlyle IV - contributor, Alex Schnell - foreword
- Narrado por: Sy Montgomery
- Duración: 4 h y 30 m
- Versión completa
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Remarkable new discoveries affirm the octopus as one of nature’s most intelligent and complex animals. This new book brings us closer than ever to these elusive creatures. The companion to the highly anticipated National Geographic television special, this book explores the alluring underwater world of the octopus—a creature that resembles an alien lifeform, but whose behavior has earned it a reputation as one of the most intelligent animals on the planet.
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An okay listen
- De Tae Bailon en 01-24-25
De: Sy Montgomery, y otros
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My Big TOE: Discovery
- Book Two of a Trilogy Unifying Philosophy, Physics, and Metaphysics
- De: Thomas Campbell
- Narrado por: Thomas Campbell
- Duración: 15 h y 25 m
- Versión completa
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Section 3 develops the interface and interaction between we the people and our digital consciousness reality. It derives and explains the characteristics, origins, dynamics, and function of ego, love, and free will. It derives our larger purpose. Finally, Section 3 develops the psi uncertainty principle as it explains and interrelates psi phenomena, free will, love, consciousness evolution, reality, human purpose, entropy and physics.
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A guidebook to a bigger reality & realization
- De Diana en 11-27-13
De: Thomas Campbell
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Letters from an Astrophysicist
- De: Neil deGrasse Tyson
- Narrado por: Neil deGrasse Tyson, Vikas Adam, Piper Goodeve, y otros
- Duración: 5 h y 35 m
- Versión completa
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Historia
Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.
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Dear Neil...
- De Tina G. en 10-14-19
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The Last Season
- De: Eric Blehm
- Narrado por: Jonathan Davis
- Duración: 12 h y 34 m
- Versión completa
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Destined to become a classic of adventure literature, The Last Season examines the extraordinary life of legendary backcountry ranger Randy Morgenson and his mysterious disappearance in California's unforgiving Sierra Nevada - mountains as perilous as they are beautiful. Eric Blehm's masterful work is a gripping detective story interwoven with the riveting biography of a complicated, original, and wholly fascinating man.
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Well Written Character Study of an NPS Ranger
- De Kathy in CA en 06-23-16
De: Eric Blehm
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Chemistry and Our Universe
- How It All Works
- De: Ron B. Davis, The Great Courses
- Narrado por: Ron B. Davis
- Duración: 30 h y 6 m
- Grabación Original
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Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.
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Great Professor, Hard to Follow.
- De Jen en 05-14-19
De: Ron B. Davis, y otros
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- De: Thomas Hager
- Narrado por: Angelo Di Loreto
- Duración: 8 h y 39 m
- Versión completa
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General
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Narración:
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Historia
Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- De C. White en 03-08-19
De: Thomas Hager
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Inspired
- How to Create Tech Products Customers Love, Second Edition
- De: Marty Cagan
- Narrado por: Marty Cagan
- Duración: 7 h y 45 m
- Versión completa
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How do today's most successful tech companies - Amazon, Google, Facebook, Netflix, Tesla - design, develop, and deploy the products that have earned the love of literally billions of people around the world? Perhaps surprisingly, they do it very differently from the vast majority of tech companies. In Inspired, technology product management thought leader Marty Cagan provides listeners with a master class in how to structure and staff a vibrant and successful product organization and how to discover and deliver technology products that your customers will love.
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Great book, terrible audio wanted to ask a refund
- De Srikanth Ramanujam en 11-15-18
De: Marty Cagan
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My Mama, Cass
- A Memoir
- De: Owen Elliot-Kugell
- Narrado por: Owen Elliot-Kugell
- Duración: 6 h y 30 m
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To the rest of the world, Cass Elliot was a rock star; A charismatic, wisecracking singer from the Rock & Roll Hall of Fame inducted band, The Mamas & The Papas; A legend of Laurel Canyon, decked out in her custom-made Muumuus, glittering designer jewelry, blessed with a powerful, instantly identifiable singing voice which helped define the sound of the 1960s counterculture movement. But to Owen Elliot-Kugell, she was just Mom. In her long-awaited memoir, Owen Elliot-Kugell shares the groundbreaking story of her mom as only a daughter can tell it.
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An Unexpected Jewel
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The Friday Afternoon Club
- A Family Memoir
- De: Griffin Dunne
- Narrado por: Griffin Dunne
- Duración: 12 h y 19 m
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At nine, Sean Connery saved him from drowning. At thirteen, desperate to hook up with Janis Joplin, he attended his aunt Joan Didion and uncle John Gregory Dunne’s legendary LA launch party for Tom Wolfe’s The Electric Kool-Aid Acid Test. At sixteen, he got kicked out of boarding school, ending his institutional education for good.
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Griffiths phrasing made it easy to listen and absorb.
- De Nancie Keay en 06-17-24
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Air Guitar
- De: Griffin Dunne
- Narrado por: Griffin Dunne
- Duración: 37 m
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These four short biographical stories of teenage delusions mainly recount the early days in actor, film director, and writer Griffin Dunne's life. Whether he's filling someone else's shoes in a new job, trying to impress an older girlfriend, or attempting to get noticed by a President, Dunne's stories are sure to engage and entertain.
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The Unclaimed
- Abandonment and Hope in the City of Angels
- De: Pamela Prickett, Stefan Timmermans
- Narrado por: Nan McNamara
- Duración: 9 h y 39 m
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In this extraordinary work of narrative nonfiction, eight years in the making, sociologists Pamela Prickett and Stefan Timmermans uncover a hidden social world. They follow four individuals in Los Angeles, tracing the twisting, poignant paths that put each at risk of going unclaimed, and introducing us to the scene investigators, notification officers, and crematorium workers who care for them when no one else will.
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Humans are complex, in life and death
- De BECreative en 01-23-25
De: Pamela Prickett, y otros
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Between Two Trailers
- A Memoir
- De: J. Dana Trent, Barbara Brown Taylor - foreword
- Narrado por: J. Dana Trent
- Duración: 7 h y 27 m
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Dana Trent is only a preschooler the first time she uses a razor blade to cut up weed and fill dime bags for her schizophrenic father, King. While King struggles with his unmedicated psychosis, Dana’s mother, the Lady, a cold and self-absorbed woman whose personality disorders rule the home, guards large bricks of drugs from the safety of their squalid trailer. But when the Lady impulsively plucks Dana from the Midwest and moves the two of them south, their fresh start results in homelessness and bankruptcy.
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An unusual and compelling story.
- De Robin Moody en 10-30-24
De: J. Dana Trent, y otros
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Another City, Not My Own
- A Novel in the Form of a Memoir
- De: Dominick Dunne
- Narrado por: Dominick Dunne
- Duración: 5 h y 17 m
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Writer, journalist and chronicler of justice as it relates to the rich and famous, Gus Bailey, like the movers and shakers of Los Angeles, is drawn into the vortex of the O. J. Simpson trial. By day, he is a fixture at the lawyers, the journalists, the hangers-on, and even the judge. By night, he is courted by the most celebrated hosts, from Kirk Douglas to Heidi Fleiss, from Elizabeth Taylor to Nancy Reagan, who delight in the hottest news from the corridors of the courtroom.
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Aother City not My Own
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De: Dominick Dunne
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My Mama, Cass
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To the rest of the world, Cass Elliot was a rock star; A charismatic, wisecracking singer from the Rock & Roll Hall of Fame inducted band, The Mamas & The Papas; A legend of Laurel Canyon, decked out in her custom-made Muumuus, glittering designer jewelry, blessed with a powerful, instantly identifiable singing voice which helped define the sound of the 1960s counterculture movement. But to Owen Elliot-Kugell, she was just Mom. In her long-awaited memoir, Owen Elliot-Kugell shares the groundbreaking story of her mom as only a daughter can tell it.
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An Unexpected Jewel
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The Friday Afternoon Club
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- De: Griffin Dunne
- Narrado por: Griffin Dunne
- Duración: 12 h y 19 m
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At nine, Sean Connery saved him from drowning. At thirteen, desperate to hook up with Janis Joplin, he attended his aunt Joan Didion and uncle John Gregory Dunne’s legendary LA launch party for Tom Wolfe’s The Electric Kool-Aid Acid Test. At sixteen, he got kicked out of boarding school, ending his institutional education for good.
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Griffiths phrasing made it easy to listen and absorb.
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De: Griffin Dunne
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Air Guitar
- De: Griffin Dunne
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These four short biographical stories of teenage delusions mainly recount the early days in actor, film director, and writer Griffin Dunne's life. Whether he's filling someone else's shoes in a new job, trying to impress an older girlfriend, or attempting to get noticed by a President, Dunne's stories are sure to engage and entertain.
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The Unclaimed
- Abandonment and Hope in the City of Angels
- De: Pamela Prickett, Stefan Timmermans
- Narrado por: Nan McNamara
- Duración: 9 h y 39 m
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In this extraordinary work of narrative nonfiction, eight years in the making, sociologists Pamela Prickett and Stefan Timmermans uncover a hidden social world. They follow four individuals in Los Angeles, tracing the twisting, poignant paths that put each at risk of going unclaimed, and introducing us to the scene investigators, notification officers, and crematorium workers who care for them when no one else will.
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Humans are complex, in life and death
- De BECreative en 01-23-25
De: Pamela Prickett, y otros
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Between Two Trailers
- A Memoir
- De: J. Dana Trent, Barbara Brown Taylor - foreword
- Narrado por: J. Dana Trent
- Duración: 7 h y 27 m
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Dana Trent is only a preschooler the first time she uses a razor blade to cut up weed and fill dime bags for her schizophrenic father, King. While King struggles with his unmedicated psychosis, Dana’s mother, the Lady, a cold and self-absorbed woman whose personality disorders rule the home, guards large bricks of drugs from the safety of their squalid trailer. But when the Lady impulsively plucks Dana from the Midwest and moves the two of them south, their fresh start results in homelessness and bankruptcy.
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An unusual and compelling story.
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De: J. Dana Trent, y otros
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Another City, Not My Own
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Writer, journalist and chronicler of justice as it relates to the rich and famous, Gus Bailey, like the movers and shakers of Los Angeles, is drawn into the vortex of the O. J. Simpson trial. By day, he is a fixture at the lawyers, the journalists, the hangers-on, and even the judge. By night, he is courted by the most celebrated hosts, from Kirk Douglas to Heidi Fleiss, from Elizabeth Taylor to Nancy Reagan, who delight in the hottest news from the corridors of the courtroom.
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Aother City not My Own
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Cloistered
- My Years as a Nun
- De: Catherine Coldstream
- Narrado por: Catherine Coldstream
- Duración: 11 h y 23 m
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Cloistered takes the listener deep into the hidden world of a traditional Carmelite monastery as it approaches the third Millennium and tells the story of an intense personal journey into and out of an enclosed life of poverty, chastity, and obedience. Finding an apparently perfect world at Akenside Priory, in Northumberland, Catherine trusts herself to a group of twenty silent women, believing she is trusting herself to God. As the beauty and mystery of an ancient way of life enfold her, she surrenders herself wholly to its power, quite unaware of the complexity and dangers that lie ahead.
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The Secret Lives of Nuns
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Did I Ever Tell You?
- A Memoir
- De: Genevieve Kingston
- Narrado por: Genevieve Kingston
- Duración: 7 h y 10 m
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Genevieve (Gwen) Kingston was just eleven years old when her mother passed away, leaving behind a chest filled with gifts and letters to celebrate the milestones of Gwen’s life and each of her birthdays until age thirty.
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Beautiful
- De Paloma M. Lee en 05-25-24
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The Masters of Medicine
- Our Greatest Triumphs in the Race to Cure Humanity's Deadliest Diseases
- De: Andrew Lam
- Narrado por: Jason Vu
- Duración: 10 h y 42 m
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Historia
Human history hinges on the battle to confront our most dangerous enemies—the half-dozen diseases responsible for killing almost all of mankind. The story of our medical triumphs reveals an inspiring tapestry of human achievement, but the journey was far from smooth. It is a tale replete with dramatic episodes as spellbinding as any blockbuster Hollywood movie. In The Masters of Medicine, Dr. Andrew Lam, an award-winning author and retinal surgeon, distills the long arc of medical progress down to the crucial moments that were responsible for the world's greatest medical miracles.
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Medical history comes to life
- De Clayton en 11-04-23
De: Andrew Lam
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American Daughter
- A Memoir
- De: Stephanie Thornton Plymale, Elissa Wald
- Narrado por: Mozhan Marno
- Duración: 9 h y 5 m
- Versión completa
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The sharp and surprising true story of a woman who finally sets out to understand her past, and the mother she had one day hoped to forget. Full of unexpected twists and unbelievable revelations, American Daughter is an immersive memoir that will have you on the edge of your seat to the very last minute.
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Amazing memoir
- De talltower4 en 09-02-21
De: Stephanie Thornton Plymale, y otros
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My Girls
- A Lifetime with Carrie and Debbie
- De: Todd Fisher
- Narrado por: Todd Fisher
- Duración: 13 h y 13 m
- Versión completa
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In December 2016, the world was shaken by the sudden deaths of Carrie Fisher and her mother Debbie Reynolds, two unspeakable losses. The stunned public turned for solace to Debbie’s only remaining child, Todd Fisher. The son of "America’s Sweethearts" Debbie Reynolds and Eddie Fisher, Todd grew up amid the glamorous wealth and pretense of Hollywood. Thanks to his mother, Todd remained down to earth, his own man, but always close to his cherished mom, and to his sister through her meteoric rise to stardom and her struggle with demons that never diminished her humor, talent, or spirit.
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Detailed & heartfelt tribute
- De Lili en 07-08-18
De: Todd Fisher
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The Swans of Harlem
- Five Black Ballerinas, Fifty Years of Sisterhood, and Their Reclamation of a Groundbreaking History
- De: Karen Valby
- Narrado por: Karlya Shelton-Benjamin, Sheila Rohan, Lydia Abarca Mitchell, y otros
- Duración: 10 h y 12 m
- Versión completa
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Historia
At the height of the Civil Rights movement, Lydia Abarca was a Black prima ballerina with a major international dance company—the Dance Theatre of Harlem, a troupe of women and men who became each other’s chosen family. She performed in some of ballet’s most iconic works with other trailblazing ballerinas, including the young women who became her closest friends—founding Dance Theatre of Harlem members Gayle McKinney-Griffith and Sheila Rohan, as well as first-generation dancers Karlya Shelton and Marcia Sells. The Swans of Harlem is a riveting account of these five accomplished women.
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An important story finally told
- De Gary en 09-23-24
De: Karen Valby
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Sociopath
- A Memoir
- De: Patric Gagne Ph.D.
- Narrado por: Patric Gagne Ph.D.
- Duración: 11 h y 7 m
- Versión completa
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General
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Historia
Patric Gagne realized she made others uncomfortable before she started kindergarten. Something about her caused people to react in a way she didn’t understand. She suspected it was because she didn’t feel things the way other kids did. Emotions like fear, guilt, and empathy eluded her. For the most part, she felt nothing. And she didn’t like the way that “nothing” felt.
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Fascinating and Perfect Performance!
- De ScoobaRubio en 04-05-24
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Consent
- A Memoir
- De: Jill Ciment
- Narrado por: Eileen Stevens
- Duración: 4 h
- Versión completa
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General
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Narración:
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Historia
In this close-up look at the ardent love affair between the author and her painting teacher, which began in the 1970s, when she was seventeen and he was forty-seven and married with two children, Ciment not only reflects on how their love ignited (who leaned in first for that kiss?) but interrogates her 1990s memoir on the subject, Half a Life. She asks herself if she told the whole truth when she wrote about their passion back then, and what truth looked like to her in the even longer-ago era of love-bead curtains when she fell in love.
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Excellent writing; overworked main question
- De Eric A. Ruthford en 06-18-24
De: Jill Ciment
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Life After Power
- Seven Presidents and Their Search for Purpose Beyond the White House
- De: Jared Cohen
- Narrado por: Kevin R. Free
- Duración: 14 h y 4 m
- Versión completa
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Historia
Former presidents have an unusual place in American life. King George III believed that George Washington’s departure after two terms made him “the greatest character of the age.” But Alexander Hamilton worried former presidents might “[wander] among the people like ghosts.” They were both right. Life After Power tells the stories of seven former presidents, from the Founding to today. Each changed history. Each offered lessons about how to decide what to do in the next chapter of life.
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Very interesting!
- De MsSew en 11-11-24
De: Jared Cohen
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A Very Private School
- A Memoir
- De: Charles Spencer
- Narrado por: Charles Spencer
- Duración: 7 h y 57 m
- Versión completa
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General
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Historia
A Very Private School offers a clear-eyed, first-hand account of a culture of cruelty at the school Charles Spencer attended in his youth and provides important insights into an antiquated boarding system. Drawing on the memories of many of his schoolboy contemporaries, as well as his own letters and diaries from the time, he reflects on the hopelessness and abandonment he felt at aged eight, viscerally describing the intense pain of homesickness and the appalling inescapability of it all.
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SO INTERESTING, SO UPSETTING, SO BELIEVABLE!
- De Mary Burnight en 03-15-24
De: Charles Spencer
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Our Hidden Conversations
- What Americans Really Think About Race and Identity
- De: Michele Norris
- Narrado por: Michele Norris, full cast
- Duración: 17 h y 44 m
- Versión completa
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Historia
The prompt seemed simple: Race. Your Story. Six Words. Please Send. The answers, though, have been challenging and complicated. In the twelve years since award-winning journalist Michele Norris first posed that question, over half a million people have submitted their stories to The Race Card Project inbox. The stories are shocking in their depth and candor, spanning the full spectrum of race, ethnicity, identity, and class. Even at just six words, the micro-essays can pack quite a punch, revealing, fear, pain, triumph, and sometimes humor.
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Excellent in every way
- De Deb Evans en 02-21-24
De: Michele Norris
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- De: Thomas Hager
- Narrado por: Angelo Di Loreto
- Duración: 8 h y 39 m
- Versión completa
-
General
-
Narración:
-
Historia
Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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-
Engrossing to physicians & lay persons alike
- De C. White en 03-08-19
De: Thomas Hager
Lo que los oyentes dicen sobre A Fatal Inheritance
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Ejecución
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Historia
- Avid reader
- 05-17-24
Powerful story told incredibly well
Cancer decimated the author's family, taking lives way too soon, way too often, as he recounts in this book. But this story is much bigger than that. It's an incredibly powerful tale, not just of his family, but of other families, of posing questions and seeking answers. The lyrical prose of his retelling reads like a novel, while his decades as a journalist with the Wall Street Journal, the New York Times, and the Los Angeles Times come through in his detailed chronicling of the journey to unwrap the medical mystery of why his branch of the family (and so many other families) have been plagued by cancer. He skillfully distills medical research into everyday language so that readers can understand the science, while he pieces in families' stories so that they can empathize with the real-life toll cancer takes on so many.
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- Charlene
- 09-27-24
Absolutely beautifully written, fascinating, poignant, tragic and unforgettable.
I am an oncology nurse practitioner and the nerd in me adores a good biomedical documentary. This is more than that, it is an odyssey, and from the moment I started it, I could not put it down. The writing is also at a level that is understandable for people without backgrounds in science, nursing or medicine.
The history of the discovery of this particularly brutal heritable cancer syndrome is absolutely fascinating and Lawrence Engrassia skillfully weaves this together with stories from the initial families studied to ascertain the cause of the syndrome with stories of his own family. The details of these families repeated suffering as family member after family member is torn from them will forever be indelibly seared into my memory.
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- Lisa Ingrassia
- 06-07-24
Stunning story and great reporting
Beautifully reported book, wonderfully read by the narrator. The book intertwines the authors story of losing his entire family to cancer with the story of the epidemiologists who discovered a cancer gene, and the families they studied on their path. This book will be interesting to anyone who has lost a family member to cancer and grappled with fear and grief around that loss.
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Historia
- Patricia Elizondo
- 07-05-24
Touching story with powerful lessons in hope.
This book provides an overview of the history of cancer diagnosis and treatments in a thoughtful way that is accessible to the non-scientific community. It sets the story context in the lives of cancer patients and their families. If you have a loved one who experienced cancer, you will cry painful tears and hopeful ones. I had to take breaks from the book, and each time it was easy to pick it back up. 🫶
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- Mildred
- 01-08-25
The research
The personal facts of these families was so honest. The cancer research into the causes of cancer was very talented.
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- patricia Caballero Rodriguez
- 01-15-25
Full of emotion
Honest and straightforward prose , full of emotion. I felt the story and learned so much as well . Worth enduring the technical parts , overall enjoyed .
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- Katherine
- 05-20-24
An important book
This book blends the heart wrenching story of the Ingrassia family and how cancer shadowed three generations with chronicling the discovery of a genetic link. Superb story telling that keeps the reader engaged even as we can anticipate the devastating outcome. The science is conveyed clearly, so that non-scientists can grasp the progress to discovering the key mutation. Engrossing, illuminating and personal.
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Historia
- Linda Thompson
- 06-02-24
An Elucidating Memoir
Mr. Ingrassia has managed to write a reader friendly treatise on cancer research that reads like a novel. With a journalist’s talent for getting to the heart of a story in a clear and concise manner, he educates the reader on the process of medical research all the while interspersing the technical issues with the very touching human stories of families, including his own, plagued by recurring cancers. This memoir is truly a masterpiece of research by the author as well as a love letter to his family.
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Historia
- mmk
- 06-05-24
Fascinating history, heartbreaking story
I am affected by an inherited genetic mutation with increased cancer risk, and an advocate for expanded germline genetic testing for more people, I feel like I am pretty knowledgeable about the topic but I did not know the backstory and history of the way researchers worked to discover and demonstrate the cancer-genetic link. It was very interesting and told in a way that was technical yet understandable - and interesting! The author wove this background history into the devastating losses in his own family that came, one after another, just a bit too early in time for the discoveries of the genetic link to be beneficial for them. I listened to this audiobook twice to absorb it all. I rarely leave reviews, but this one touched me. I hope it is read widely and that even one family will take a closer look at their family experience with cancer and inquire about germline testing - it could save the lives of the current and next generations.
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Historia
- Kristin V. Johnson
- 08-11-24
A Layman's Explanation of Cancer
I walked away from this book with an easily understood history of cancer, its causes, and treatments. I would highly recommend this book to anyone who wants to learn more or has a history of cancer in the family.
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