Hacking the Code of Life
How Gene Editing Will Rewrite Our Futures
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Narrado por:
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Karen Cass
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De:
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Nessa Carey
Acerca de esta escucha
Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year.
But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.
But is it ethical to change the genetic material of organisms in a way that might be passed on to future generations? If a person is suffering from a lethal genetic disease, is it even more unethical to deny them this option? Who controls the application of this technology, when it makes "biohacking" - perhaps of one’s own genome - a real possibility?
Nessa Carey’s book is a thrilling and timely snapshot of a technology that will radically alter our futures.
©2019 by Nessa Carey. (P)2019 Brilliance Publishing, Inc., all rights reserved.Los oyentes también disfrutaron...
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Historia
Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- De Howard Sterling en 06-29-16
De: Daniel M. Davis
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The Deeper Genome
- Why There Is More to the Human Genome than Meets the Eye
- De: John Parrington
- Narrado por: John Lee
- Duración: 9 h
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Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.
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Great Scientific Writing/ Wrong Narrator
- De Richard en 11-24-15
De: John Parrington
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Sicker, Fatter, Poorer
- The Urgent Threat of Hormone-Disrupting Chemicals on Our Health and Future . . . and What We Can Do About It
- De: Leonardo Trasande MD MPP
- Narrado por: Leonardo Trasande MD MPP
- Duración: 6 h y 44 m
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Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.
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The Must Read Book of 2019 is here early on Audio!
- De Ryan S en 12-21-18
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p53: The Gene That Cracked the Cancer Code
- De: Sue Armstrong
- Narrado por: Elizabeth Jasicki
- Duración: 9 h y 55 m
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p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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Excellent story! Unfortunate narration at start
- De Adriana en 12-25-14
De: Sue Armstrong
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The Gene
- An Intimate History
- De: Siddhartha Mukherjee
- Narrado por: Dennis Boutsikaris
- Duración: 19 h y 22 m
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The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
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It's a Wonderful Book
- De JKC en 06-02-16
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- De: George Johnson
- Narrado por: Arthur Morey
- Duración: 8 h y 19 m
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- De Digital Dilema en 09-06-13
De: George Johnson
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The Truth About Cancer
- De: Ty M. Bollinger
- Narrado por: Ty M. Bollinger
- Duración: 9 h y 11 m
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One out of three women alive today, and one out of two men, will face a cancer diagnosis, according to the World Health Organization. Ty Bollinger takes this personally: in the course of a decade, he says, "I lost my entire family to cancer. I don't believe I had to lose them." The Truth about Cancer has been written for one simple reason: to share the knowledge we need to protect ourselves, treat ourselves, and in some cases save our lives or the lives of those we love.
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save a life with this valuable information.
- De edwin matias en 12-30-16
De: Ty M. Bollinger
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How to Clone a Mammoth
- The Science of De-Extinction
- De: Beth Shapiro
- Narrado por: Coleen Marlo
- Duración: 7 h y 13 m
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Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.
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Very Readable Take on a Complex Subject
- De John en 04-26-15
De: Beth Shapiro
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Life Unfolding
- How the Human Body Creates Itself
- De: Jamie A. Davies
- Narrado por: Napoleon Ryan
- Duración: 9 h y 56 m
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Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?
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Fascinating Biology ; Distracting Narration
- De Tim en 03-01-15
De: Jamie A. Davies
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Between Hope and Fear
- A History of Vaccines and Human Immunity
- De: Michael Kinch
- Narrado por: Mel Foster
- Duración: 15 h y 59 m
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Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Michael Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent - and could easily be undone. Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.
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Enjoyed
- De Minsi Zhang en 05-03-20
De: Michael Kinch
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Viruses, Plagues, and History
- Past, Present, and Future
- De: Michael B. A. Oldstone
- Narrado por: L.J. Ganser
- Duración: 13 h y 38 m
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The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.
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very detailed, but very statistical
- De ekhensel15 en 01-12-19
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The Story of the Human Body
- Evolution, Health, and Disease
- De: Daniel E. Lieberman
- Narrado por: Sean Runnette
- Duración: 14 h y 54 m
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In this landmark book of popular science, Daniel E. Lieberman - chair of the department of human evolutionary biology at Harvard University and a leader in the field - gives us a lucid and engaging account of how the human body evolved over millions of years, even as it shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning this paradox: greater longevity but increased chronic disease.
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Could Have Been Good, but...
- De Trebla en 04-08-18
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Herding Hemingway's Cats
- Understanding How Our Genes Work
- De: Kat Arney
- Narrado por: Kat Arney
- Duración: 8 h y 39 m
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The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?
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A non-scientists misguided interpretation
- De AraSevera en 05-15-16
De: Kat Arney
Lo que los oyentes dicen sobre Hacking the Code of Life
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- Philip Savva
- 04-30-22
Bang ! Crack ! Swashbucklers will save us ..
Info-audicted, finally someone raising the roof. Here's the arthritis cure & how it is done.
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- Joel
- 02-23-23
Not captivating nor intriguing story at all.
Content is good, updated, talks about innovation and in depth in the topic. However, Not captivating nor intriguing story at all.
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- Stephen H
- 01-20-24
A brief dip of the toe
I cannot say that this was bad, but it was not exactly what I expected. In 4 2/3 hours, the book manages a brief overview of gene editing and its potential impacts on life in the future.
After a brief introduction, the author focuses on gene editing using CRISPR; no surprise here. She does not really say much about how CRISPR works, and spends more time on patent battles than on the scientific details. While she discusses some of the ways genes have been edited or could be edited, and the purpose of such changes, this is really quite perfunctory.
The book simply seems to lack a clear purpose and focus, and so one bounces from one idea to the next without an overarching narrative. It was okay, but not great.
The narrator was good, with no major missteps.
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- Linda S.
- 02-08-23
Enjoyable listen
As a farm wife I am increasingly shocked by the general publics ignorance about “GMOs”. I appreciate this opportunity to educate myself further about this very important topic.
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- RickyF
- 03-31-23
okay book
lots of info here. if this topic is unfamiliar then it is worth reading.
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- A. Toomey
- 06-18-20
Decent Overview. Could lose sarcasm.
This book starts out with a lot of snark and sarcasm. I'm assuming the intention is to provide humor, but for me it was too thickly laid on for a science book even one meant for the mainstream. Thankfully, by chapter two it does thin down to the occasional comment or jab at this group or that situation.
Overall the content generally lines up with what I know of the field, though I'm no expert. At times she does raise some interesting questions and conundrums which will need to be addressed as the science moves forward. If you're looking for a broad overview of the field this succeeds in that regard, though as others have noted, with a field moving along so quickly how long this information remains current is anyone's guess.
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esto le resultó útil a 5 personas
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- Donita
- 02-15-23
Good layman insight to complex issue
I have enormously high hopes for CRISPR for personal reasons & I want the technology to hurry up and get here, but this book opened my eyes to the known unknowns & made me aware of unintended consequences. I have great respect for the scientific community that is working so hard to try to help what has been beyond help. I thought this book did a good job of illustrating all aspects of this miraculous leap forward in our collective knowledge.
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- sct
- 07-04-19
Great survey on the state of the art of genetics
I listened this book in rapid succession after 'The Gene' by Siddhartha Mukherjee and Nessa''s previous book "The Epigentics Revolution". I'd highly recommend this trio if you want to get a good grounder on this topic.
I felt that the book did a great job reviewing the state of the art of this area of science. Not only the science, but also gave insights into the regulatory difficulties, the people behind the science and she even touched on some of the ethical issues. She succeeded in being balanced and even - i.e., no moral preening that was present in other books on this topic. Probably the most sensationalistic part of the book is the title - but authors sometimes don't get to choose this.
I saw another post about the audio being bad - I had no such complaints.
The only fear I have about this book is that because the science is moving so quickly, it may have a short shelf life. So...listen to it now!
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esto le resultó útil a 4 personas
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- Rick B
- 05-22-21
A New World
This is an excellent listen from Audible as it reflects on the history of an emerging technology that has the power to change the world. The narration by Karen Cass is perfect. If you enjoy learning and appreciate the value of truth, then I believe that this investment will not disappoint you. The near future is ours to control. Will we do it responsibly or change our species by mistake. There are very deep possibilities within Gene editing. We could help feed the hungry, prevent disease and stop the incredible pain that some people must feel just to be alive. There is so much we could do to make positive change, but the possibility for negative change is beyond our understanding. I highly recommend this book, The narrator has a very English accent, I think that adds to the over all value as the listener is more inclined to listen carefully to the message. 5 Stars all the way!
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esto le resultó útil a 2 personas
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- Pete D
- 10-14-19
Wonderfull Book
Well done so a layman can understand. Very current information in a fast moving field.
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