The deep-learning revolution has brought us driverless cars, the greatly improved Google Translate, fluent conversations with Siri and Alexa, and enormous profits from automated trading on the New York Stock Exchange. Deep-learning networks can play poker better than professional poker players and defeat a world champion at Go. In this book, Terry Sejnowski explains how deep learning went from being an arcane academic field to a disruptive technology in the information economy.

You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.

Dip below the ocean’s surface and you are soon confronted by forms of life that could not seem more foreign to our own: sea sponges, soft corals, and serpulid worms, whose rooted bodies, intricate geometry, and flower-like appendages are more reminiscent of plant life or even architecture than anything recognizably animal. Yet these creatures are our cousins. As fellow members of the animal kingdom — the Metazoa— they can teach us much about the evolutionary origins of not only our bodies, but also our minds.

An enchanting biography of the most resonant - and most necessary - chemical element on Earth. Carbon. It's in the fibers in your hair, the timbers in your walls, the food that you eat, and the air that you breathe. It's worth billions as a luxury and half a trillion as a necessity, but there are still mysteries yet to be solved about the element that can be both diamond and coal. Where does it come from, what does it do, and why, above all, does life need it?

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

When leading Princeton physicist Paul Steinhardt began working in the 1980s, scientists thought they knew all the conceivable forms of matter. The Second Kind of Impossible is the story of Steinhardt’s 35-year-long quest to challenge conventional wisdom. It begins with a curious geometric pattern that inspires two theoretical physicists to propose a radically new type of matter - one that raises the possibility of new materials with never-before-seen properties but that violates laws set in stone for centuries.

Carl Zimmer investigates one of the biggest questions of all: What is life? The answer seems obvious until you try to seriously answer it. Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can’t answer that question here on Earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society’s most charged conflicts - whether a fertilized egg is a living person, for example, and when we ought to declare a person legally dead.

Infinite Powers recounts how calculus tantalized and thrilled its inventors, starting with its first glimmers in ancient Greece and bringing us right up to the discovery of gravitational waves. Strogatz reveals how this form of math rose to the challenges of each age: how to determine the area of a circle with only sand and a stick; how to explain why Mars goes "backwards" sometimes; how to turn the tide in the fight against AIDS.

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

When we talk about human history, we often focus on great leaders, population forces, and decisive wars. But how has the earth itself determined our destiny? Our planet wobbles, driving changes in climate that forced the transition from nomadism to farming. Mountainous terrain led to the development of democracy in Greece. Atmospheric circulation patterns later on shaped the progression of global exploration, colonization, and trade. Even today, voting behavior in the southeast United States ultimately follows the underlying pattern of 75 million-year-old sediments from an ancient sea.

A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

When leading Princeton physicist Paul Steinhardt began working in the 1980s, scientists thought they knew all the conceivable forms of matter. The Second Kind of Impossible is the story of Steinhardt’s 35-year-long quest to challenge conventional wisdom. It begins with a curious geometric pattern that inspires two theoretical physicists to propose a radically new type of matter - one that raises the possibility of new materials with never-before-seen properties but that violates laws set in stone for centuries.

In How the Laser Happened, Nobel laureate Charles Townes provides a highly personal look at some of the leading events in 20th-century physics. This lively memoir, packed with firsthand accounts and historical anecdotes, is an invaluable resource for anyone interested in the history of science and an inspiring example for students considering scientific careers.

Lee Hood did that rarest of things. He enabled scientists to see things they couldn't see before and do things they hadn't dreamed of doing. Scientists can now sequence complete human genomes in a day, setting in motion a revolution that is personalizing medicine. Hood, a son of the American West, was an unlikely candidate to transform biology. But with ferocious drive, he led a team at Caltech that developed the automated DNA sequencer, the tool that paved the way for the Human Genome Project.

In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.

The Pleasure of Finding Things Out is a magnificent treasury of the best short works of Richard P. Feynman, from interviews and speeches to lectures and printed articles. A sweeping, wide-ranging collection, it presents an intimate and fascinating view of a life in science - a life like no other. From his ruminations on science in our culture to his Nobel Prize acceptance speech, this book will delight anyone interested in the world of ideas.

Robert Oppenheimer was among the most brilliant and divisive of men. As head of the Los Alamos Laboratory, he oversaw the successful effort to beat the Nazis in the race to develop the first atomic bomb – a breakthrough that was to have eternal ramifications for mankind and that made Oppenheimer the “Father of the Atomic Bomb.” But with his actions leading up to that great achievement, he also set himself on a dangerous collision course with Senator Joseph McCarthy and his witch-hunters. In Robert Oppenheimer: A Life Inside the Center, Ray Monk, author of peerless biographies of Ludwig Wittgenstein and Bertrand Russell, goes deeper than any previous biographer in the quest to solve the enigma of Oppenheimer’s motivations and his complex personality.

Nine remarkable men produced inventions that changed the world. The printing press, the telephone, powered flight, recording and others have made the modern world what it is. But who were the men who had these ideas and made reality of them? As David Angus shows, they were very different - quiet, boisterous, confident, withdrawn - but all had a moment of vision allied to single-minded determination to battle through numerous prototypes and produced something that really worked. This is a fascinating account for younger listeners.

Paul Dirac was among the great scientific geniuses of the modern age. One of the discoverers of quantum mechanics, the most revolutionary theory of the past century, his contributions had a unique insight, eloquence, clarity, and mathematical power. His prediction of antimatter was one of the greatest triumphs in the history of physics.

From one of our most acclaimed science writers: a dramatic narrative of the discovery of the true nature and startling size of the universe, delving back past the moment of revelation to trace the decades of work--by a select group of scientists--that made it possible.

p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

A brilliantly original and richly illuminating exploration of entanglement, the seemingly telepathic communication between two separated particles - one of the fundamental concepts of quantum physics.

In this hugely entertaining sequel to the New York Times best-selling memoir An Appetite for Wonder, Richard Dawkins delves deeply into his intellectual life spent kick-starting new conversations about science, culture, and religion and writing yet another of the most audacious and widely read books of the 20th century - The God Delusion.

American taxpayers spend $30 billion annually funding biomedical research, but over half of these studies can't be replicated due to poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence for terminal patients. In Rigor Mortis, Richard Harris explores these urgent issues with vivid anecdotes, personal stories, and interviews with the top biomedical researchers. We need to fix our dysfunctional biomedical system - before it's too late.

Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.

Oxygen takes the listener on an enthralling journey, as gripping as a thriller, as it unravels the unexpected ways in which oxygen spurred the evolution of life and death.

An enchanting biography of the most resonant - and most necessary - chemical element on Earth. Carbon. It's in the fibers in your hair, the timbers in your walls, the food that you eat, and the air that you breathe. It's worth billions as a luxury and half a trillion as a necessity, but there are still mysteries yet to be solved about the element that can be both diamond and coal. Where does it come from, what does it do, and why, above all, does life need it?

The knowledge of death is so terrifying that we live most of our lives in denial of it. One of the most difficult moments of childhood must be when each of us first realizes that not only we but all our loved ones will die—and there is nothing we can do about it. Or at least, there hasn’t been. Today, we are living through a revolution in biology. Giant strides are being made in understanding why we age—and why some species live longer than others. Could we eventually cheat disease and death and live for a very long time, possibly many times our current lifespan?

A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

For modern science, the transitional states of consciousness lie at the forefront of research in many fields. For a Buddhist practitioner, these same states present crucial opportunities to explore and transform consciousness itself. This book is the account of a historic dialogue between leading Western scientists and the Dalai Lama of Tibet. Revolving around three key moments of consciousness - sleep, dreams, and death - the conversations recorded here are both engrossing and highly listenable.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

In this fascinating and thought-provoking book, author Nick Lane brings together the latest research findings in the exciting field of mitochondria research to reveal how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death.

You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.