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Raised as an oversized elf, Buddy travels from the North Pole to New York City to meet his biological father, Walter Hobbs, who doesn't know he exists and is in desperate need of some Christmas spirit.

After months of isolation, Isherwood "Ish" Williams, learns that most of the world has fallen to a mysterious illness. Yet, despite his instincts to further isolate, Ish leads the charge to develop a new civilization.

As the world teeters on the brink of annihilation, Dietrich Bonhoeffer joins a deadly plot to assassinate Hitler, risking his faith and fate to save millions of Jews from genocide.

A crew of miniature aliens operate a spaceship that has a human form. While trying to save their planet, the aliens encounter a new problem, as their ship becomes smitten with an Earth woman.

Santos, a failed comic book artist, lives in a parallel universe where he's a superhero who has to save the world.

A middle-aged pediatrician finds himself to be out of step with his son, an internist, who wishes his father weren't so old-fashioned.

Two opposites form an unlikely friendship.

Ish, a solitary young geologist, barely survives a snake bite; after he wakes from a coma, he drives to the nearest town only to find dead bodies; he searches for survivors, from San Francisco to Las Vegas.

Ish finds a survivor, Emma. There's a spark. Is it real, or are they just the last two people on earth? Nature is unrelenting. Rats plague San Lupo. Ish dreams of rebuilding civilization, but can they even survive extinction?

New survivors appear but Ish doesn't trust them, Emma invites them in; a bad storm slams San Lupo.

A drought hits San Lupo; a nomadic group arrives that knows how to find water and want to trade; Ish has his doubts, but chooses to accept help.

San Lupo fights for survival against the virus. Ish realizes the answers to humanity's future may not be in his books. That's when Ish finds Joey's secret project. There must be others out there. Joey might just hold the key.

Ish catches Charlie assaulting Evie so San Lupo must decide how to punish evil; the virus returns and Joey falls ill; Ish feels humanity's future hanging in the balance.