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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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New study uncovers how genes influence retinal aging and brain health

Researchers at the Jackson Laboratories used mice with nine different genetic backgrounds to identify factors influencing eye aging, paving the way for eye-based diagnostics for neurodegenerative diseases

NEI study: New take on old marker of cell death

New findings from a National Eye Institute-led study add a twist on how a widely used cell death marker, annexin-V, can be interpreted in the lab and the clinic for tracking retinal cell death in eye diseases such as glaucoma.

CRISPR gene editing promising for blinding disease retinitis pigmentosa

National Eye Institute-funded scientists using gene editing corrected a mutation in a mouse model of retinitis pigmentosa, an inherited blinding eye disorder. The gene editing strategy restored production of rhodopsin, and retinal function and structure
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Social determinants of health associated with diabetic eye-care quality

New data demonstrate how social determinants of health can fuel disparities in monitoring for diabetic retinopathy for patients of different racial and ethnic groups.
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University of Nebraska researchers show role of cytokines in retinal cells

NEI-funded team demonstrates for the first time that cytokines play an important role in the development and regeneration of the retinal cells that degenerate in glaucoma.
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U. Minnesota researchers discover potential new pathway to prevent age-related macular degeneration

The team identified small molecules that can reduce the production of proteins linked to age-related macular degeneration.

Discovery in hibernating animals could extend the shelf life of cells and tissues for transplantation  

Research led by scientists at the National Eye Institute and Sun Yat-sen University, Guangzhou, China points to a potential strategy for extending the cold storage shelf life of donor cells and tissues, such as those of the pancreas.
Mouse retinal blood vessels

How neurons build a 3-D vascular structure to keep the retina healthy

Researchers at UC San Francisco have found a new type of neuron that guides the formation of a lattice of blood vessels nourishes cells in the retina.
Schematic of Mouse arrestin-1 gene.

Study suggests high-frequency electrical ‘noise’ results in congenital night blindness

Findings from mouse study indicate how one mutation of rhodopsin may cause congenital stationary night blindness in humans.
microscopic image of a COVID-19 virion

COVID-19 virus could damage vision

Researchers at the University of Missouri School of Medicine have discovered that the virus that causes COVID-19 can breach the blood-retina barrier with potential long-term consequences in the eye.

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