News

Dr Vladimir Volkov awarded Wellcome Trust Career Development Grant

Faculty of Science and Engineering  Centre for Molecular Cell Biology 

6 December 2024

3D reconstruction of growing and shortening microtubule ends, revealing protofilament organization and dynamics. Credit by: M. Kalutskii et. al. / bioarxiv.org (https://doi.org/10.1101/2024.11.04.621893)
3D reconstruction of growing and shortening microtubule ends, revealing protofilament organization and dynamics. Credit by: M. Kalutskii et. al. / bioarxiv.org (https://doi.org/10.1101/2024.11.04.621893)

Dr Vladimir Volkov of Centre for Molecular Cell Biology has been awarded the Wellcome Trust Career Development Award to support his research on the "Structural and mechanistic understanding of kinetochore-mediated control of microtubule dynamics". This significant funding will enable Dr Volkov's laboratory to explore the molecular intricacies of kinetochore-microtubule interactions, vital for processes like cell division and migration.

The project aims to unravel how kinetochores - a complex assembly of proteins - regulate and balance microtubule dynamics under force. By employing cutting-edge techniques such as electron cryo-tomography and a combination of light and electron microscopy, his research will shed light on the mechanisms underlying this force-sensitive connection. The work also promises insights into post-translational regulation and evolutionary conservation of these processes.

Dr Volkov said: "Very happy to receive a Wellcome Trust Career Development Award! The award will fund my lab for a whopping eight years, allowing us to dissect force-sensing at the kinetochore-microtubule interface in depth using a variety of biochemical, structural, and imaging methods."

Dr Volkov is also looking to expand his team, with a postdoctoral position opening in 2025. Interested researchers are encouraged to visit the Queen Mary jobs portal for details.

Contact: Dr Vladimir Volkov
Email: v.volkov@qmul.ac.uk

Updated by: David Lockwood